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OrthoMTA¿Í ProRoot MTAÀÇ Ç׹̻ý¹° È¿°ú ºñ±³

COMPARISON OF ANTIMICROBIAL EFFECTS OF ORTHOMTA AND PROROOT MTA

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±è¼ö¿µ ( Kim Soo-Yung ) - Àü³²´ëÇб³ Ä¡ÀÇÇÐÀü¹®´ëÇпø ¼Ò¾ÆÄ¡°úÇб³½Ç
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¹ÚÁöÀÏ ( Park Ji-Il ) - ±¤ÁÖº¸°Ç´ëÇб³ Ä¡À§»ý°ú
±è¼±¹Ì ( Kim Seon-Mi ) - Àü³²´ëÇб³ Ä¡ÀÇÇÐÀü¹®´ëÇпø ¼Ò¾ÆÄ¡°úÇб³½Ç

Abstract

º» ¿¬±¸ÀÇ ¸ñÀûÀº ÇöÀç ¸¹ÀÌ »ç¿ëµÇ°í ÀÖ´Â ProRoot MTA (Dentsply Tulsa, USA)¿Í ÃÖ±Ù ±¹³»¿¡¼­ »õ·Î °³¹ßµÈ OrthoMTA (Bio MTA, Korea)ÀÇ °¨¿°µÈ ±Ù°ü¿¡¼­ ÁÖ·Î ¹ß°ßµÇ´Â 3°³ÀÇ ¹Ì»ý¹°¿¡ ´ëÇÑ È¿°ú¸¦ ´Ù¾çÇÑ ³óµµ¿Í ½Ã°£¿¡¼­ ºñ±³ÇÏ´Â °ÍÀÌ´Ù. 50, 25, 12.5 mg/mLÀÇ ³óµµ·Î ÁغñµÈ ProRoot MTA¿Í OrthoMTA¿¡ Enterococcus faecalis, Fusobacterium nucleatum ±×¸®°í Staphylococcus epidermidis¸¦ Á¢Á¾ ÈÄ 24, 48, 72½Ã°£¿¡ Ç׹̻ý¹° È¿°ú¸¦ °üÂûÇÏ¿© ´ÙÀ½°ú °°Àº ¿¬±¸°á°ú¸¦ ¾ò¾ú´Ù. E. faecalisÀÇ °æ¿ì ProRoot MTA¿Í OrthoMTA 50, 25, 12.5 mg/mL ³óµµÀÇ ¸ðµç ½Ã°£´ë¿¡¼­ ¼¼±ÕÀ» ¿ÏÀüÈ÷ ¾ïÁ¦ÇÏÁö´Â ¸øÇßÁö¸¸ ¾ç¼º ´ëÁ¶±º¿¡ ºñÇØ ¼ºÀåÀÌ Á¶±Ý °¨¼ÒÇÑ ¾ç»óÀ» º¸¿´´Ù(p < 0.05). F. nucleatumÀÇ °æ¿ì ProRoot MTA 50 mg/mL ³óµµÀÇ 24½Ã°£¿¡¼­ ¹Ì»ý¹°À» ¾ïÁ¦ÇÏ¿´À¸³ª ½Ã°£ÀÌ Áö³²¿¡ µû¶ó ¼¼±ÕÀÇ ¼ºÀåÀ» º¸ÀÎ ¹Ý¸é OrthoMTAÀÇ °æ¿ì °°Àº ³óµµ¿¡¼­ ½Ã°£ÀÌ Áö³ªµµ °è¼Ó ¼¼±ÕÀ» ¾ïÁ¦ÇÏ¿´´Ù(p < 0.05). S. epidermidisÀÇ °æ¿ì ProRoot MTA 50 mg/mL, OrthoMTA 50, 25 mg/mL ³óµµÀÇ 24½Ã°£¿¡¼­ ¾ïÁ¦ È¿°ú¸¦ º¸¿´À¸³ª ½Ã°£ÀÌ Áö³ª¸é¼­ ¼¼±ÕÀÌ Á¶±Ý¾¿ ¼ºÀåÇÏ¿´´Ù. ±×·¯³ª ÀüüÀûÀ¸·Î ¸ðµç ³óµµ¿Í ½Ã°£¿¡¼­ ¾ç¼º ´ëÁ¶±º¿¡ ºñÇؼ­´Â ¾ïÁ¦ È¿°ú¸¦ ³ªÅ¸³Â´Ù(p < 0.05). º» ¿¬±¸¸¦ ÅëÇØ ±¹³»¿¡¼­ »õ·Î °³¹ßµÈ OrthoMTA´Â ±âÁ¸ÀÇ ProRoot MTAº¸´Ù Ç×±ÕÈ°¼ºÀ» °¡Áö°í ÀÖÀ½À» ¾Ë ¼ö ÀÖ¾ú´Ù.

The aim of this study was to compare two commercial root canal medicaments, ProRoot MTA (Dentsply Tulsa, USA) and OrthoMTA (Bio MTA, Korea), by assessing the antimicrobial effects on three selected species commonly found in root canals of infected teeth, namely Enterococcus faecalis, Fusobacterium nucleatum and Staphylococcus epidermidis. Colonies of these bacteria were treated with varied concentrations of ProRoot MTA or OrthoMTA over different lengths of time. The results are as follows : 50, 25 and 12.5 mg/mL of ProRoot MTA or OrthoMTA did not completely inhibit the growth of E. faecalis, but a decreased growth rate was evident in comparison to the control (p < 0.05). 50 mg/mL of both materials successfully eliminated F. nucleatum during the first 24 hours. Regrowth of microbes after 24 hours, however, indicated a diminished effect of ProRoot MTA whereas OrthoMTA showed its continuously sustained antimicrobial actions (p < 0.05). 50 mg/mL of ProRoot MTA and 50, 25 mg/mL of OrthoMTA exerted their full antibacterial actions against S. epidermidis during the first 24 hours. Although the regrowth of colony was observed after 24 hours, the rate of growth was significantly decreased, approximating a complete inhibition (p < 0.05). The present study revealed that OrthoMTA, recently developed in Korea, had antimicrobial activity higher than ProRoot MTA.

Å°¿öµå

Ç× ¹Ì»ý¹° È¿°ú; OrthoMTA; ProRoot MTA
Antimicrobial effects; OrthoMTA; ProRoot MTA

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